I personally have 1 cat Peewee who has the lounge and kitchen while we are away, If we didn't the other cats lives would be hell when he has his urges and jumps on anything that moves. Jessica, Teddy and Jeanie have our bedroom the hall landing and staircase. Brindle Leg and Gypsy also have access to those during the day but at night they are placed in the smaller bedroom. They all appear fine and happy and after the first day it gets easy for whoever is caring for them to know the routine.